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Tools to better understand biology by tapping information in phylogenies
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Comparison of 9 macroevolutionary models: Compare the fit of 9 different macroevolutionary models that transform a phylogram: all possible combinations of these two types of transformations: type 1: transform tree to be phylogenetic (as input), non-phylogenetic (star), or punctuated (one of the two descendant edges of a node has length zero) and type 2: nonzero branches with length proportional to genetic distance, all lengths equal, or all lengths optimized based on the phenotypic character


Citations(s) (based on web hits only through time [why]):

Citation chart


Reference(s):

Todd H Oakley, X Gu, E Abouheif, N H Patel, and Ming Li 2005 "Comparative methods for the analysis of gene-expression evolution: An example using yeast functional genomic data" Molecular Biology and Evolution 22(1): 40-50


Criteria :

  • Likelihood


Questions addressed by the method:

  • Compare model fits for single character (Evaluate which of several evolutionary models best describes the evolution of some trait). Topic area: Parameter estimation or model selection for character model


Character combinations addressed by the method:

  • Continuous unbounded-None-None


Software implementing the method:

  • COMET (CoMET stands for Continuous-character Model Evaluation and Testing and is a module for the Mesquite Project. Give it a tree topology as a starting point and some phenotypic data, CoMET tells you the likelihoods of the data evolving through nine different evolutionary models.) [open source]